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Tel: 646-831-8792 (PST)
E-Mail: david.hh.n@gmail.com

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PUBLICATIONS \\​

RESEARCH ARTICLES

[17] Tang J, Huang Y, Nguyen DH, Costes SV, Snijders AM, Mao JH. "Genetic background modulates lncRNA-modulated tissue response to low dose ionizing radiation." International Journal of Genomics February 2015.

[16] Nguyen DH, Ouyang H, Mao JH, Hlatky L, and Barcellos-Hoff MH. "Distinct luminal type mammary carcinomas arise from orthotopic Trp53 null mammary transplantation of juvenile versus adult mice." Cancer Research 2014; Oct. 3, Published OnlineFirst

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[15] Nguyen DH. "Thyroid inflammation associates with down-regulation of FOXE1 and enrichment for a stem cell transcriptome implicating epithelial dedifferentiation as a mechanism of thyroid cancer risk due to thyroiditis." Abstract reported at the 2nd World Congress on Thyroid Cancer, July 10-14, 2013 (Toronto, Canada). [Manuscript in preparation]

[14] Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruiz H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes SV, Barcellos-Hoff MH. "Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors." Stem Cells 2013; Aug 23.


[13] Nguyen DH, Zhou T, Shu J, and Mao JH (2013). “Quantifying chromogen intensity in immunohistochemistry via reciprocal intensity.” Cancer InCytes 2(1):e.

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[12] Nguyen DH, Fredlund E, Zhao W, Perou C, Balmain A, Mao JH, Barcellos-Hoff MH. (2013). Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes. Clinical Cancer Research 19(6):1353-62.

[11] Lee DY, Bowen B, Nguyen DH, Parsa S, Huang Y, Mao JH, Northen T (2012). Low-dose ionizing radiation-induced blood plasma response in a diverse genetic mouse population. Radiation Research 178(6):551-5.

[10] Nguyen DH, Zhou T, Shu J, Hua H, Mao JH. (2012). Two applications of a fluorescent chromogen in immunohistochemistry of formalin-fixed paraffin-embedded tissue sections to overcome common limitations of detection. Cancer InCytes 1(1):e.

[9] Nguyen DH. (2011). Stromal Modulation of Radiation Carcinogenesis in Breast Cancer." ProQuest/UMI (Ann Arbor). Doctoral Dissertation.

[8] Nguyen DH, Oketch-Rabah HA, Illa-Bochaca I, Geyer FC, Reis-Filho JS, Mao JH, Ravani SA, Zavadil J, Borowsky AD, Jerry DJ, Dunphy KA, Seo JH, Haslam S, Medina D, Barcellos-Hoff MH. (2011). Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type. Cancer Cell 19, 640-651.

[7] Nguyen DH, Bochaca II, Barcellos-Hoff MH. (2011) "The Biological Impact of Radiation Exposure on Breast Cancer Development." The Environment and Breast Cancer. Jose Russo (ed.). Springer (New York). pp 185-203.

[6] Nguyen DH, Martinez-Ruiz H, Barcellos-Hoff MH. (2011). Consequences of Epithelial or Stromal TGFbeta1 Depletion in the Mammary Gland. J Mammary Gland Biol Neoplasia 16, 147-155.

[5] Barcellos-Hoff MH, Nguyen DH. (2009). Radiation carcinogenesis in context: how do irradiated tissues become tumors? Health Physics 97(5):446-57.

[4] Nguyen HH, Lavrenov SN, Sundar SN, Nguyen DH, Tseng M, Marconett CN, Kung J, Staub RE, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL (2010). 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells. Chemical Biological Interactions 186(3):255-66.

[3] Nguyen HH, Aronchik I, Brar GA, Nguyen DH, Bjeldanes LF, Firestone GL (2008). The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing. Proceedings of the National Academy of Sciences 105(50): 19750-5.

[2] Costes SV, Ponomarev A, Chen JL, Nguyen D, Cucinotta FA, Barcellos-Hoff MH (2007). Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Computational Biology (8): e155.

[1] Garcia HH, Brar GA, Nguyen DH, Bjeldanes LF, Firestone GL (2005). Indole-3-carbinol (I3C) inhibits cyclin-dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin E forms, and subcellular localization of the CDK2 protein complex. Journal of Biological Chemistry 280(10): 8756-64. 

BOOKS

Systems Biology of Tumor Physiology: Rethinking the Past, Defining the Future.

Springer Science+Business Media. New York, 2015.

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